Gap-AF AFNET 1 Trial

Title

Catheter ablation of arial fibrillation by linear pulmonary vein isolation

Summary

A randomized trial to investigate the significance of complete versus incomplete electrical isolation of pulmonary veins by radiofrequency-induced linear lesions in patients with paroxysmal atrial fibrillation

Number of Patients

233

Coordinating Investigator

Prof. Karl-Heinz Kuck, Hamburg, Germany

Current Status

completed

Funding

German Federal Ministry of Education and Research

Publications

Kuck KH, Hoffmann BA, Ernst S, Wegscheider K, Treszl A, Metzner A, Eckardt L, Lewalter T, Breithardt G, Willems S; Gap-AF–AFNET 1 Investigators. Impact of complete versus incomplete circumferential lines around the pulmonary veins during catheter ablation of paroxysmal atrial fibrillation: Results from the Gap-AF – AFNET 1 trial. Circ Arrhythm Electrophysiol. 2016 Apr; 4: 514 - 522; 9:e003337. DOI: 10.1161/CIRCEP.115.003337 . (first published online 2016 Jan 13)

Sauer W, Callans D. The Tribulations of Atrial Fibrillation Ablation Trialists (Editorial). Circ Arrhythm Electrophysiol. 2016; 9:e003738. DOI: 10.1161/CIRCEP.115.003738

Registration

www.clinicaltrials.gov/ct2/show/NCT00293943