Molecular causes of AF
Title
Molecular and electrophysiological causes of atrial fibrillation in a transgenic model (CREM-IbDC-X-transgenic mouse)
Coordinating Investigator
Prof. Paulus Kirchhof, Birminham, UK
Overall Responsibility
Kompetenznetz Vorhofflimmern - Competence Network on Atrial Fibrillation
Current Status
completed
Funding:
German Federal Ministry of Education and Research
Publications
Kirchhof P, Marijon E, Fabritz L, Li N, Wang W, Wang T, Schulte K, Hanstein J, Schulte JS, Vogel M, Mougenot N, Laakmann S, Fortmueller L, Eckstein J, Verheule S, Kaese S, Staab A, Grote-Wessels S, Schotten U, Moubarak G, Wehrens XH, Schmitz W, Hatem S, Müller FU. Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice. Int J Cardiol. 2011; 166; 366–74. DOI:10.1016/j.ijcard.2011.10.057.